/
Français
English
No description
UE21 Neurophysiology of aging
ECUE's code : SMUSVI21
EUR LIFE
Biochimie et biologie moléculaire
,
Neurosciences
,
Biologie cellulaire
Campus Valrose
Master 1
,
Master 2
Semestre pair
Anglais
PRESENTATION
Life expectancy is increasing world-wide, thus raising the challenge of preventing physical and cognitive disabilities.
The course of Neurophysiology of Aging will focus on the neurophysiology of healthy aging, in order to understand cellular modifications associated to age-related neuropathologies.
The course is structured in three big topics:
(1) age-related sensorial modifications (input),
(2) age-related alterations of the central nervous system (integration and coordination) and age-related changes of the neuromuscular system (output).
In the end of this course, the student will be able to integrate the multiple age-related modifications, correlating molecular and cellular alterations with physiological consequences at the organism level.
---------------------------------------------------------------------------------------
Speakers and Associated Research Labs
- Paula Pousinha IPMC UMR 7275
- Bruno Cessac INRIA Biovision Laboratory
- Aurèlie Calabrèse LPC UMR 7290
- Michel Hoen Oticon Medical
- Jérémie Topin ICN UMR 7272
- Anne Baron IPMC UMR 7275
- Fréderic Checler IPMC UMR 7275
- Mounia Chami IPMC UMR 7275
- Miguel Godinho Ferreira IRCAN
- Luisa Vaqueiro Lopes IMM, FML – Portugal
- Loic Broussot – CHU Nice
----------------------------------------------------------------------------------------
Threated themes
- Introduction to neurophysiology of aging
- Brain aging
- Neuroaging in a petri dish
- Visual system
- Auditory system and language
- Gustation and olfactation: therapeutic approach to Alzheimer’s disease?
- Pain
- Dementias and cognitive decline
- Sleep and circadian rythms
- Basal ganglia and psychiatric disorders in aging
- Neurodegenerative disorder
- Neuromuscular disorders associated with aging
- Pre-clinical research in the context of aging
In parallel with master classes, the students will have theoretical practical classes in which they will be challenged to write and present an Exploratory Research Project. Briefly, the students will be guided through the different steps of scientific project design: Question, scientific context, hypothesis, experimental model(s) and experimental
Course's manager(s)
, Paula Pousinha
In class
- 28h of lectures
- 4h of directed studies
- 4h of practical work
PREREQUISITES
No prerequisite
OBJECTIVES
By the end of this course, I should be able to...
- integrate the multiple age-related modifications, correlating molecular and cellular alterations with physiological consequences at the organism level.
CONTENT
-
Neurophysiology of aging - intro
-
Brain aging hallmarks
No description
-
Visual system
No description
-
Auditory system and language
No description
-
Gustation and olfaction
No description
-
Pain
No description
-
Dementias
No description
-
Circadian Rythms
No description
-
Alzheimer's disease
No description
-
Parkinson's disease
No description
-
Stroke and cerebral vascular accident
No description
-
Pre-clinical research in the context of aging
No description
-
Aged neuromuscular synapse
No description
-
Activity and physical performance upon ageing
No description
-
Exploratory research project : form question to communication skills
No description
Access to complete Syllabus (Authentification required)
Important
This syllabus has no contractual value. Its content is subject to change throughout this year: be aware to the last updates